SOX12 antibody (AA 40-120)

Catalog No. ABIN7224430

The Rabbit Polyclonal anti-SOX12 antibody is suitable to detect SOX12 in samples from Human and Mouse. It has been validated for ELISA and IHC (p).

Quick Overview for SOX12 antibody (AA 40-120) (ABIN7224430)

Target: SOX12 (SRY (Sex Determining Region Y)-Box 12 (SOX12))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX12 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-SOX12 Antibody

Binding Specificity: AA 40-120

Purpose: Sox-12 Polyclonal Antibody

Specificity: Sox-12 Polyclonal Antibody detects endogenous levels of Sox-12 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human Sox-12 at AA range: 40-120

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for SOX12

Target: SOX12 (SRY (Sex Determining Region Y)-Box 12 (SOX12))

Alternative Name: Sox-12

Background: Rabbit Anti-Sox-12 Polyclonal Antibody,SOX12, SOX22, Transcription factor SOX-12, Protein SOX-22,Members of the SOX family of transcription factors are characterized by the presence of a DNA-binding high mobility group (HMG) domain, homologous to the HMG box of sex-determining region Y (SRY). Forming a subgroup of the HMG domain superfamily, SOX proteins have been implicated in cell fate decisions in a diverse range of developmental processes. SOX transcription factors have diverse tissue-specific expression patterns during early development and have been proposed to act as target-specific transcription factors and/or as chromatin structure regulatory elements. The protein encoded by SOX12 (SRY-box 12) was identified as a SOX family member based on conserved domains, and its expression in various tissues suggests a role in both differentiation and maintenance of several cell types.,Transcription factor SOX-12

Gene ID: 6666

UniProt: O15370