Stanniocalcin 1 antibody
Quick Overview for Stanniocalcin 1 antibody (ABIN7231558)
Target
See all Stanniocalcin 1 (STC1) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- STC1 Polyclonal Antibody
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Specificity
- The antibody detects endogenous levels of STC1 protein
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogen
- Synthesized peptide derived from part region of human STC1 protein
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Stanniocalcin 1 (STC1)
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Alternative Name
- STC1
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Background
- Rabbit Anti-STC1 Polyclonal Antibody,Stanniocalcin-1,STC1 encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. STC1 contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. STC1 has altered expression in hepatocellular, ovarian, and breast cancers.,STC1
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Molecular Weight
- observerd band 27kDa
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Gene ID
- 6781
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UniProt
- P52823
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Pathways
- Hormone Activity
Target
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