Stathmin 1 antibody (pSer16)

Catalog No. ABIN7213068

The Rabbit Polyclonal anti-Stathmin 1 antibody has been validated for WB, ELISA, IF and IHC (p). It is suitable to detect Stathmin 1 in samples from Human, Mouse and Rat.

Quick Overview for Stathmin 1 antibody (pSer16) (ABIN7213068)

Target: Stathmin 1 (STMN1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Stathmin 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Stathmin 1 Antibody

Binding Specificity: pSer16

Purpose: Op18 (phospho Ser16) Polyclonal Antibody

Specificity: Phospho-Op18 (S16) Polyclonal Antibody detects endogenous levels of Op18 protein only when phosphorylated at S16.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human Op18 Phospho-Ser16

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Stathmin 1

Target: Stathmin 1 (STMN1)

Alternative Name: Op18

Background: Rabbit Anti-Op18 (phospho Ser16) Polyclonal Antibody,STMN1, C1orf215, LAP18, OP18, Stathmin, Leukemia-associated phosphoprotein p18, Metablastin, Oncoprotein 18, Op18, Phosphoprotein p19, pp19, Prosolin, Protein Pr22, pp17,STMN1 belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. Stathmin 1 is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Multiple transcript variants encoding different isoforms have been found for STMN1.,Stathmin

Molecular Weight: observerd band 17kDa

Gene ID: 3925

UniProt: P16949

Pathways: MAPK Signaling, Microtubule Dynamics