ST5 antibody (AA 380-460)

Catalog No. ABIN7217128

This anti-ST5 antibody is a Rabbit Polyclonal antibody detecting ST5 in WB and ELISA. Suitable for Human and Mouse.

Quick Overview for ST5 antibody (AA 380-460) (ABIN7217128)

Target: ST5 (Suppression of Tumorigenicity 5 (ST5))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ST5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ST5 Antibody

Binding Specificity: AA 380-460

Purpose: ST5 Polyclonal Antibody

Specificity: ST5 Polyclonal Antibody detects endogenous levels of ST5 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human ST5 at AA range: 380-460

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for ST5

Target: ST5 (Suppression of Tumorigenicity 5 (ST5))

Alternative Name: ST5

Background: Rabbit Anti-ST5 Polyclonal Antibody,ST5, DENND2B, HTS1, Suppression of tumorigenicity 5 protein, DENN domain-containing protein 2B, HeLa tumor suppression 1,ST5 was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. Suppression of tumorigenicity 5 protein encoded by ST5 contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified.,Suppression of tumorigenicity 5 protein

Molecular Weight: observerd band 126kDa

Gene ID: 6764

UniProt: P78524