SYN2 antibody (AA 370-450)

Catalog No. ABIN7231614

The Rabbit Polyclonal anti-SYN2 antibody has been validated for WB and ELISA. It is suitable to detect SYN2 in samples from Mouse, Human and Rat.

Quick Overview for SYN2 antibody (AA 370-450) (ABIN7231614)

Target: SYN2 (Synapsin II (SYN2))

Reactivity: Mouse, Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYN2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SYN2 Antibody

Binding Specificity: AA 370-450

Purpose: SYN2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of SYN2 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human SYN2 protein at AA range: 370-450

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for SYN2

Target: SYN2 (Synapsin II (SYN2))

Alternative Name: SYN2

Background: Rabbit Anti-SYN2 Polyclonal Antibody,Synapsin-2, Synapsin II,SYN2 is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family encodes a neuron-specific phosphoprotein that selectively binds to small synaptic vesicles in the presynaptic nerve terminal. Polymorphisms in SYN2 are associated with abnormal presynaptic function and related neuronal disorders, including autism, epilepsy, bipolar disorder and schizophrenia. Alternative splicing of SYN2 results in multiple transcript variants. The tissue inhibitor of metalloproteinase 4 gene is located within an intron of SYN2 and is transcribed in the opposite direction.,SYN2

Molecular Weight: observerd band 64kDa

Gene ID: 6854

UniProt: Q92777