Syndecan 2 antibody (AA 50-130)

Catalog No. ABIN7224190

The Rabbit Polyclonal anti-Syndecan 2 antibody has been validated for WB and ELISA. It is suitable to detect Syndecan 2 in samples from Human.

Quick Overview for Syndecan 2 antibody (AA 50-130) (ABIN7224190)

Target: Syndecan 2 (SDC2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Syndecan 2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Syndecan 2 Antibody

Binding Specificity: AA 50-130

Purpose: Syndecan-2 Polyclonal Antibody

Specificity: Syndecan-2 Polyclonal Antibody detects endogenous levels of Syndecan-2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human Syndecan-2 at AA range: 50-130

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Syndecan 2

Target: Syndecan 2 (SDC2)

Alternative Name: Syndecan-2

Background: Rabbit Anti-Syndecan-2 Polyclonal Antibody,SDC2, HSPG1, Syndecan-2, SYND2, Fibroglycan, Heparan sulfate proteoglycan core protein, HSPG, CD antigen CD362,The protein encoded by SDC2 (syndecan 2) is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types.,Syndecan-2

Molecular Weight: observerd band 22kDa

Gene ID: 6383

UniProt: P34741

Pathways: Glycosaminoglycan Metabolic Process