STXBP1 antibody (pSer313)

Catalog No. ABIN7224550

This Rabbit Polyclonal antibody specifically detects STXBP1 in WB and ELISA. It exhibits reactivity toward Human, Mouse, Rat and Monkey.

Quick Overview for STXBP1 antibody (pSer313) (ABIN7224550)

Target: STXBP1 (Syntaxin Binding Protein 1 (STXBP1))

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STXBP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-STXBP1 Antibody

Binding Specificity: pSer313

Purpose: Unc18-1 (phospho Ser313) Polyclonal Antibody

Specificity: Phospho-Unc18-1 (S313) Polyclonal Antibody detects endogenous levels of Unc18-1 protein only when phosphorylated at S313.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human Unc18-1 Phospho-Ser313

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for STXBP1

Target: STXBP1 (Syntaxin Binding Protein 1 (STXBP1))

Alternative Name: Unc18-1

Background: Rabbit Anti-Unc18-1 (phospho Ser313) Polyclonal Antibody,STXBP1, UNC18A, Syntaxin-binding protein 1, MUNC18-1, N-Sec1, Protein unc-18 homolog 1, Unc18-1, Protein unc-18 homolog A, Unc-18A, p67,STXBP1 (syntaxin binding protein 1) encodes a syntaxin-binding protein. The encoded protein appears to play a role in release of neurotransmitters via regulation of syntaxin, a transmembrane attachment protein receptor. Mutations in STXBP1 have been associated with infantile epileptic encephalopathy-4. Alternatively spliced transcript variants have been described.,Syntaxin-binding protein 1

Molecular Weight: observerd band 65kDa

Gene ID: 6812

UniProt: P61764

Pathways: Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport