TBX3 antibody (AA 270-350)

Catalog No. ABIN7224616

The Rabbit Polyclonal anti-TBX3 antibody has been validated for WB and ELISA. It is suitable to detect TBX3 in samples from Human, Mouse and Rat.

Quick Overview for TBX3 antibody (AA 270-350) (ABIN7224616)

Target: TBX3 (T-Box 3 (TBX3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBX3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TBX3 Antibody

Binding Specificity: AA 270-350

Purpose: TBX3 Polyclonal Antibody

Specificity: TBX3 Polyclonal Antibody detects endogenous levels of TBX3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human TBX3 at AA range: 270-350

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for TBX3

Target: TBX3 (T-Box 3 (TBX3))

Alternative Name: TBX3

Background: Rabbit Anti-TBX3 Polyclonal Antibody,TBX3, T-box transcription factor TBX3, T-box protein 3,TBX3 (T-box 3) is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in TBX3 cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of TBX3 results in three transcript variants encoding different isoforms, however, the full length nature of one variant has not been determined.,T-box transcription factor TBX3

Molecular Weight: observerd band 79kDa

Gene ID: 6926

UniProt: O15119

Pathways: Hormone Transport, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development