tau antibody (pSer214)

Catalog No. ABIN7222330

The Rabbit Polyclonal anti-tau antibody has been validated for WB and ELISA. It is suitable to detect tau in samples from Human, Mouse and Rat.

Quick Overview for tau antibody (pSer214) (ABIN7222330)

Target: tau (tau Protein)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This tau antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-tau Antibody

Binding Specificity: pSer214

Purpose: Tau (phospho Ser214) Polyclonal Antibody

Specificity: Phospho-Tau (S214) Polyclonal Antibody detects endogenous levels of Tau protein only when phosphorylated at S214.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human Tau Phospho-Ser214

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for tau

Target: tau (tau Protein)

Alternative Name: Tau

Background: Rabbit Anti-Tau (phospho Ser214) Polyclonal Antibody,MAPT, MAPTL, MTBT1, TAU, Microtubule-associated protein tau, Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau,MAPT encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.,Microtubule-associated protein tau

Molecular Weight: observerd band 50-85kDa

Gene ID: 4137

UniProt: P10636