TEAD2 antibody (AA 40-120)

Catalog No. ABIN7225436

This Rabbit Polyclonal antibody specifically detects TEAD2 in ELISA, WB, IF and IHC (p). It exhibits reactivity toward Human and Mouse.

Quick Overview for TEAD2 antibody (AA 40-120) (ABIN7225436)

Target: TEAD2 (TEA Domain Family Member 2 (TEAD2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TEAD2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-TEAD2 Antibody

Binding Specificity: AA 40-120

Purpose: TEF-4 Polyclonal Antibody

Specificity: TEF-4 Polyclonal Antibody detects endogenous levels of TEF-4 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human TEF-4 at AA range: 40-120

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for TEAD2

Target: TEAD2 (TEA Domain Family Member 2 (TEAD2))

Alternative Name: TEF-4

Background: Rabbit Anti-TEF-4 Polyclonal Antibody,TEAD2, TEF4, Transcriptional enhancer factor TEF-4, TEA domain family member 2, TEAD-2,The Hippo pathway is an important evolutionarily conserved signaling pathway that controls organ size and tumor suppression by inhibiting cell proliferation and promoting apoptosis. An integral function of the Hippo pathway is to repress the activity of Yes-associated protein (YAP), a proposed oncogene whose activity is regulated by phosphorylation and subcellular localization. When the Hippo pathway is turned off, YAP is phosphorylated and translocates to the nucleus where it associates with various transcription factors including members of the transcriptional enhancer factor (TEF) family, also known as the TEA domain (TEAD) family (TEAD1-4). Although widely expressed in tissues, the TEAD family proteins have specific tissue and developmental distributions. YAP/TEAD complexes regulate the expression of genes involved in cell proliferation and apoptosis.,Transcriptional enhancer factor TEF-4

Gene ID: 8463

UniProt: Q15562

Pathways: Regulation of Lipid Metabolism by PPARalpha, Tube Formation