Tenascin N antibody

Catalog No. ABIN7231754

This Rabbit Polyclonal antibody specifically detects Tenascin N in ELISA and WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for Tenascin N antibody (ABIN7231754)

Target: Tenascin N (TNN)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tenascin N antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-Tenascin N Antibody

Purpose: TENN Polyclonal Antibody

Specificity: The antibody detects endogenous levels of TENN protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human TENN protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Tenascin N

Target: Tenascin N (TNN)

Alternative Name: TENN

Background: Rabbit Anti-TENN Polyclonal Antibody,Tenascin-N, TN-N, Tenascin-W, TN-W,TNN (Tenascin N) is a Protein Coding gene. Diseases associated with TNN include Adhesive Otitis Media and Chronic Purulent Otitis Media. Among its related pathways are ECM proteoglycans and Focal Adhesion. Extracellular matrix protein that seems to be a ligand for ITGA8: ITGB1, ITGAV: ITGB1 and ITGA4: ITGB1. Involved in neurite outgrowth and cell migration in hippocampal explants. During endochondral bone formation, inhibits proliferation and differentiation of proteoblasts mediated by canonical WNT signaling. In tumors, stimulates angiogenesis by elongation, migration and sprouting of endothelial cells. Expressed in most mammary tumors, may facilitate tumorigenesis by supporting the migratory behavior of breast cancer cells.,TENN

Molecular Weight: observerd band 142kDa

Gene ID: 63923

UniProt: Q9UQP3

Pathways: ACE Inhibitor Pathway