Tensin 1 antibody (pTyr1326)

Catalog No. ABIN7213348

This Rabbit Polyclonal antibody specifically detects Tensin 1 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for Tensin 1 antibody (pTyr1326) (ABIN7213348)

Target: Tensin 1 (TNS1)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tensin 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Tensin 1 Antibody

Binding Specificity: pTyr1326

Purpose: Tensin-1 (phospho Tyr1326) Polyclonal Antibody

Specificity: Phospho-Tensin-1 (Y1326) Polyclonal Antibody detects endogenous levels of Tensin-1 protein only when phosphorylated at Y1326.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human Tensin-1 Phospho-Tyr1326

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Tensin 1

Target: Tensin 1 (TNS1)

Alternative Name: Tensin-1

Background: Rabbit Anti-Tensin-1 (phospho Tyr1326) Polyclonal Antibody,TNS1, TNS, Tensin-1,Tensin 1 encoded by TNS1 localizes to focal adhesions, regions of the plasma membrane where the cell attaches to the extracellular matrix. This protein crosslinks actin filaments and contains a Src homology 2 (SH2) domain, which is often found in molecules involved in signal transduction. Tensin 1 is a substrate of calpain II. Alternative splicing results in multiple transcript variants encoding different isoforms.,Tensin-1

Molecular Weight: observerd band 185kDa

Gene ID: 7145

UniProt: Q9HBL0