TGIF2 antibody

Catalog No. ABIN7231776

This Rabbit Polyclonal antibody specifically detects TGIF2 in ELISA and WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for TGIF2 antibody (ABIN7231776)

Target: TGIF2 (TGFB-Induced Factor Homeobox 2 (TGIF2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TGIF2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-TGIF2 Antibody

Purpose: TGIF2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of TGIF2 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human TGIF2 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for TGIF2

Target: TGIF2 (TGFB-Induced Factor Homeobox 2 (TGIF2))

Alternative Name: TGIF2

Background: Rabbit Anti-TGIF2 Polyclonal Antibody,Homeobox protein TGIF2, 5'-TG-3'-interacting factor 2, TGF-beta-induced transcription factor 2, TGFB-induced factor 2,TGIF2 (TGFB Induced Factor Homeobox 2) is a Protein Coding gene. Diseases associated with TGIF2 include Holoprosencephaly 4. Among its related pathways are Transcriptional activity of SMAD2/SMAD3-SMAD4 heterotrimer and mir34a and TGIF2 in osteoclastogenesis. The protein encoded by TGIF2 is a DNA-binding homeobox protein and a transcriptional repressor, which appears to repress transcription by recruiting histone deacetylases to TGF beta-responsive genes. TGIF2 is amplified and over-expressed in some ovarian cancers. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. Read-through transcription also exists between TGIF2 and the neighboring downstream C20orf24 (chromosome 20 open reading frame 24) gene.,TGIF2

Molecular Weight: observerd band 26kDa

Gene ID: 60436

UniProt: Q9GZN2