THBS4 antibody (AA 551-600)
Quick Overview for THBS4 antibody (AA 551-600) (ABIN7231788)
Target
See all THBS4 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 551-600
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Purpose
- Thrombospondin 4 Polyclonal Antibody
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Specificity
- The antibody detects endogenous levels of Thrombospondin 4
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogen
- Synthesized peptide derived from part region of human Thrombospondin 4 protein at AA range: 551-600
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:200), ELISA (1:10000-1:20000).
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- THBS4 (Thrombospondin 4 (THBS4))
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Alternative Name
- Thrombospondin 4
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Background
- Rabbit Anti-Thrombospondin 4 Polyclonal Antibody,Thrombospondin-4,The protein encoded by THBS4 belongs to the thrombospondin protein family. Thrombospondin family members are adhesive glycoproteins that mediate cell-to-cell and cell-to-matrix interactions. This protein forms a pentamer and can bind to heparin and calcium. It is involved in local signaling in the developing and adult nervous system, and it contributes to spinal sensitization and neuropathic pain states. THBS4 is activated during the stromal response to invasive breast cancer. It may also play a role in inflammatory responses in Alzheimer's disease. Alternative splicing results in multiple transcript variants. THBS4 (Thrombospondin 4) is a Protein Coding gene. Diseases associated with THBS4 include Mycetoma and Myocardial Infarction. Among its related pathways are Focal Adhesion and PI3K-Akt signaling pathway.,Thrombospondin 4
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Gene ID
- 7060
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UniProt
- P35443
Target
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