TRIP12 antibody (AA 950-1030)

Catalog No. ABIN7231912

This anti-TRIP12 antibody is a Rabbit Polyclonal antibody detecting TRIP12 in WB and ELISA. Suitable for Human, Mouse and Rat.

Quick Overview for TRIP12 antibody (AA 950-1030) (ABIN7231912)

Target: TRIP12 (Thyroid Hormone Receptor Interactor 12 (TRIP12))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIP12 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TRIP12 Antibody

Binding Specificity: AA 950-1030

Purpose: TRIPC Polyclonal Antibody

Specificity: The antibody detects endogenous levels of TRIPC protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human TRIPC protein at AA range: 950-1030

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for TRIP12

Target: TRIP12 (Thyroid Hormone Receptor Interactor 12 (TRIP12))

Alternative Name: TRIPC

Background: Rabbit Anti-TRIPC Polyclonal Antibody,E3 ubiquitin-protein ligase TRIP12, E3 ubiquitin-protein ligase for Arf, ULF, HECT-type E3 ubiquitin transferase TRIP12, Thyroid receptor-interacting protein 12, TR-interacting protein 12, TRIP-12,TRIP12 (Thyroid Hormone Receptor Interactor 12) is a Protein Coding gene. Diseases associated with TRIP12 include Non-Syndromic Intellectual Disability and Chronic Dacryocystitis. Among its related pathways are Class I MHC mediated antigen processing and presentation and Ubiquitin mediated proteolysis. The protein encoded by TRIP12 is an E3 ubiquitin-protein ligase involved in the degradation of the p19ARF/ARF isoform of CDKN2A, a tumor suppressor. The encoded protein also plays a role in the DNA damage response by regulating the stability of USP7, which regulates tumor suppressor p53.,TRIPC

Molecular Weight: observerd band 219kDa

Gene ID: 9320

UniProt: Q14669

Pathways: Nuclear Hormone Receptor Binding