TLE1/2/3/4 (AA 721-770) antibody
Quick Overview for TLE1/2/3/4 (AA 721-770) antibody (ABIN7226814)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 721-770
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Purpose
- TLE1/2/3/4 Polyclonal Antibody
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Specificity
- TLE1/2/3/4 Polyclonal Antibody detects endogenous levels of TLE1/2/3/4.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from TLE1/2/3/4 at AA range: 721-770
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- TLE1/2/3/4
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Background
- Rabbit Anti-TLE1/2/3/4 Polyclonal Antibody,similar to transducin-like enhancer of split 1/2/3/4,Transducin-like enhancer of split proteins (TLE1, TLE2, TLE3, TLE4, and TLE6) are mammalian homologs of Drosophila Groucho. TLEs contain several WD-repeats implicated in protein-protein interaction. TLEs are transcriptional co-repressors that bind to many transcription factors such as LEF1, Runx1, Oct-1, hepatocyte nuclear factor 3-β as well as histone H3. TLEs are differentially expressed during animal development and may have overlapping as well as distinct functions.,TLE1
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Molecular Weight
- observerd band 90kDa
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Gene ID
- 7088
Target
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