TM2D1 antibody

Catalog No. ABIN7231836

The Rabbit Polyclonal anti-TM2D1 antibody (ABIN7231836) specifically detects TM2D1 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for TM2D1 antibody (ABIN7231836)

Target: TM2D1 (TM2 Domain Containing 1 (TM2D1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TM2D1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TM2D1 Antibody

Purpose: TM2D1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of TM2D1 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human TM2D1 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for TM2D1

Target: TM2D1 (TM2 Domain Containing 1 (TM2D1))

Alternative Name: TM2D1

Background: Rabbit Anti-TM2D1 Polyclonal Antibody,TM2 domain-containing protein 1, Amyloid-beta-binding protein, hBBP,The protein encoded by TM2D1 is a beta-amyloid peptide-binding protein. It contains a structural module related to that of the seven transmembrane domain G protein-coupled receptor superfamily and known to be important in heterotrimeric G protein activation. Beta-amyloid peptide has been established to be a causative factor in neuron death and the consequent diminution of cognitive abilities observed in Alzheimer's disease. This protein may be a target of neurotoxic beta-amyloid peptide, and may mediate cellular vulnerability to beta-amyloid peptide toxicity through a G protein-regulated program of cell death. Several transcript variants have been found for TM2D1.,TM2D1

Molecular Weight: observerd band 22kDa

Gene ID: 83941

UniProt: Q9BX74