TNIP3 antibody (AA 40-120)

Catalog No. ABIN7231850

This Rabbit Polyclonal antibody specifically detects TNIP3 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for TNIP3 antibody (AA 40-120) (ABIN7231850)

Target: TNIP3 (TNFAIP3 Interacting Protein 3 (TNIP3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNIP3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TNIP3 Antibody

Binding Specificity: AA 40-120

Purpose: TNIP3 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of TNIP3 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human TNIP3 protein at AA range: 40-120

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for TNIP3

Target: TNIP3 (TNFAIP3 Interacting Protein 3 (TNIP3))

Alternative Name: TNIP3

Background: Rabbit Anti-TNIP3 Polyclonal Antibody,TNFAIP3-interacting protein 3, A20-binding inhibitor of NF-kappa-B activation 3, ABIN-3, Listeria-induced gene protein,TNIP3 (TNFAIP3 Interacting Protein 3) is a Protein Coding gene. Among its related pathways are Ovarian tumor domain proteases and Immune response IL-23 signaling pathway. Binds to zinc finger protein TNFAIP3 and inhibits NF-kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13-acetate. Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding.,TNIP3

Molecular Weight: observerd band 35kDa

Gene ID: 79931

UniProt: Q96KP6

Pathways: Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin