TRRAP antibody

Catalog No. ABIN7231932

The Rabbit Polyclonal anti-TRRAP antibody is suitable to detect TRRAP in samples from Human and Mouse. It has been validated for IHC (p).

Quick Overview for TRRAP antibody (ABIN7231932)

Target: TRRAP (Transformation/transcription Domain-Associated Protein (TRRAP))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRRAP antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-TRRAP Antibody

Purpose: TRRAP Polyclonal Antibody

Specificity: The antibody detects endogenous levels of TRRAP protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human TRRAP protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:300).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for TRRAP

Target: TRRAP (Transformation/transcription Domain-Associated Protein (TRRAP))

Alternative Name: TRRAP

Background: Rabbit Anti-TRRAP Polyclonal Antibody,Transformation/transcription domain-associated protein, 350/400 kDa PCAF-associated factor, PAF350/400, STAF40, Tra1 homolog,TRRAP (Transformation/Transcription Domain Associated Protein) encodes a large multidomain protein of the phosphoinositide 3-kinase-related kinases (PIKK) family. The encoded protein is a common component of many histone acetyltransferase (HAT) complexes and plays a role in transcription and DNA repair by recruiting HAT complexes to chromatin. Deregulation of TRRAP may play a role in several types of cancer including glioblastoma multiforme. Alternatively spliced transcript variants encoding multiple isoforms have been observed for TRRAP.,TRRAP

Molecular Weight: observerd band 424kDa

Gene ID: 8295

UniProt: Q9Y4A5