TGFBR3 antibody

Catalog No. ABIN7224682

This anti-TGFBR3 antibody is a Rabbit Polyclonal antibody detecting TGFBR3 in WB, ELISA and IHC (p). Suitable for Human, Mouse and Rat.

Quick Overview for TGFBR3 antibody (ABIN7224682)

Target: TGFBR3 (Transforming Growth Factor, beta Receptor III (TGFBR3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TGFBR3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-TGFBR3 Antibody

Purpose: TGFβ RIII Polyclonal Antibody

Specificity: TGFβ RIII Polyclonal Antibody detects endogenous levels of TGFβ RIII protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human TGFbeta RIII around the non-phosphorylation site of T842

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for TGFBR3

Target: TGFBR3 (Transforming Growth Factor, beta Receptor III (TGFBR3))

Alternative Name: TGFbeta RIII

Background: Rabbit Anti-TGFβ RIII Polyclonal Antibody,TGFBR3, Transforming growth factor beta receptor type 3, TGF-beta receptor type 3, TGFR-3, Betaglycan, Transforming growth factor beta receptor III, TGF-beta receptor type III,TGFBR3 (transforming growth factor beta receptor 3) encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for TGFBR3.,Transforming growth factor beta receptor type 3

Gene ID: 7049

UniProt: Q03167