TMEM185A antibody (AA 260-340)
Quick Overview for TMEM185A antibody (AA 260-340) (ABIN7225424)
Target
See all TMEM185A AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 260-340
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Purpose
- TMEM185A Polyclonal Antibody
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Specificity
- TMEM185A Polyclonal Antibody detects endogenous levels of TMEM185A protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from the C-terminal region of human TMEM185A at AA range: 260-340
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- TMEM185A (Transmembrane Protein 185A (TMEM185A))
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Alternative Name
- TMEM185A
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Background
- Rabbit Anti-TMEM185A Polyclonal Antibody,TMEM185A, CXorf13, FAM11A, Transmembrane protein 185A, Protein FAM11A,The protein encoded by TMEM185A (transmembrane protein 185A) is predicted to be a transmembrane protein. TMEM185A is best known for localizing to the CpG island of the fragile site FRAXF. The 5' untranslated region of this gene contains a CGG trinucleotide repeat sequence that normally consists of 7-40 tandem CGG repeats but which can expand to greater than 300 repeats. Methylation of the CpG island leads to transcriptional silencing of this gene, but neither the silencing nor an expanded repeat region appear to manifest itself in a clear phenotypic manner. Alternative splicing results in multiple transcript variants. A pseudogene of TMEM185A has been defined on the X chromosome.,Transmembrane protein 185A
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Molecular Weight
- observerd band 41kDa
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Gene ID
- 84548
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UniProt
- Q8NFB2
Target
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