TMEM185A antibody (N-Term)

Catalog No. ABIN5517081

This Rabbit Polyclonal antibody specifically detects TMEM185A in WB. It exhibits reactivity toward Human, Mouse, Cow, Dog, Guinea Pig, Horse, Rat and Zebrafish (Danio rerio).

Quick Overview for TMEM185A antibody (N-Term) (ABIN5517081)

Target: TMEM185A (Transmembrane Protein 185A (TMEM185A))

Reactivity: Human, Mouse, Cow, Dog, Guinea Pig, Horse, Rat, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMEM185A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TMEM185A Antibody

Binding Specificity: N-Term

Sequence: RNPQYRAEGE TCVEFKAMLI AVGIHLLLLM FEVLVCDRIE RGSHFWLLVF

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against T185A. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen for Anti-TMEM185A antibody is: synthetic peptide directed towards the N-terminal region of Human T185A

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TMEM185A

Target: TMEM185A (Transmembrane Protein 185A (TMEM185A))

Alternative Name: TMEM185A

Background: The protein encoded by this gene is predicted to be a transmembrane protein. This gene is best known for localizing to the CpG island of the fragile site FRAXF. The 5' untranslated region of this gene contains a CGG trinucleotide repeat sequence that normally consists of 7-40 tandem CGG repeats but which can expand to greater than 300 repeats. Methylation of the CpG island leads to transcriptional silencing of this gene, but neither the silencing nor an expanded repeat region appear to manifest itself in a clear phenotypic manner. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on the X chromosome.

Alias Symbols: ee3, FRAXF, FAM11A, CXorf13

Protein Size: 350

Gene ID: 84548

NCBI Accession: NP_115897

UniProt: Q8NFB2