TUBGCP4 antibody (AA 160-240)

Catalog No. ABIN7215030

This Rabbit Polyclonal antibody specifically detects TUBGCP4 in ELISA, WB and IHC (p). It exhibits reactivity toward Human and Mouse.

Quick Overview for TUBGCP4 antibody (AA 160-240) (ABIN7215030)

Target: TUBGCP4 (Tubulin, gamma Complex Associated Protein 4 (TUBGCP4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TUBGCP4 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-TUBGCP4 Antibody

Binding Specificity: AA 160-240

Purpose: GCP4 Polyclonal Antibody

Specificity: GCP4 Polyclonal Antibody detects endogenous levels of GCP4 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human GCP4 at AA range: 160-240

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for TUBGCP4

Target: TUBGCP4 (Tubulin, gamma Complex Associated Protein 4 (TUBGCP4))

Alternative Name: GCP4

Background: Rabbit Anti-GCP4 Polyclonal Antibody,TUBGCP4, 76P, GCP4, Gamma-tubulin complex component 4, GCP-4, hGCP4, Gamma-ring complex protein 76 kDa, h76p, hGrip76,TUBGCP4 encodes a component of the gamma-tubulin ring complex, gamma-tubulin complex component 4, which is required for microtubule nucleation. In mammalian cells, the protein localizes to centrosomes in association with gamma-tubulin. Crystal structure analysis revealed a structure composed of five helical bundles arranged around conserved hydrophobic cores. An exposed surface area located in the C-terminal domain is essential and sufficient for direct binding to gamma-tubulin. Mutations in this gene that alter microtubule organization are associated with microcephaly and chorioretinopathy. Alternative splicing results in multiple transcript variants.,Gamma-tubulin complex component 4

Molecular Weight: observerd band 76kDa

Gene ID: 27229

UniProt: Q9UGJ1

Pathways: M Phase