TYR antibody (AA 440-520)

Catalog No. ABIN7217416

This Rabbit Polyclonal antibody specifically detects TYR in WB and ELISA. It exhibits reactivity toward Human and Monkey.

Quick Overview for TYR antibody (AA 440-520) (ABIN7217416)

Target: TYR (Tyrosinase (TYR))

Reactivity: Human, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TYR antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TYR Antibody

Binding Specificity: AA 440-520

Purpose: TYR Polyclonal Antibody

Specificity: TYR Polyclonal Antibody detects endogenous levels of TYR protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human TYR at AA range: 440-520

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for TYR

Target: TYR (Tyrosinase (TYR))

Alternative Name: TYR

Background: Rabbit Anti-TYR Polyclonal Antibody,TYR, Tyrosinase, LB24-AB, Monophenol monooxygenase, SK29-AB, Tumor rejection antigen AB,The enzyme encoded by TYR catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene.,Tyrosinase

Molecular Weight: observerd band 80kDa

Gene ID: 7299

UniProt: P14679