USP36 antibody (AA 470-550)
Quick Overview for USP36 antibody (AA 470-550) (ABIN7223810)
Target
See all USP36 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 470-550
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Purpose
- USP36 Polyclonal Antibody
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Specificity
- USP36 Polyclonal Antibody detects endogenous levels of USP36 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from the Internal region of human USP36 at AA range: 470-550
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- USP36 (Ubiquitin Specific Peptidase 36 (USP36))
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Alternative Name
- USP36
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Background
- Rabbit Anti-USP36 Polyclonal Antibody,USP36, KIAA1453, Ubiquitin carboxyl-terminal hydrolase 36, Deubiquitinating enzyme 36, Ubiquitin thioesterase 36, Ubiquitin-specific-processing protease 36,USP36 (ubiquitin specific peptidase 36) encodes a member of the peptidase C19 or ubiquitin-specific protease family of cysteine proteases. Members of this family remove ubiquitin molecules from polyubiquitinated proteins. The encoded protein may deubiquitinate and stabilize the transcription factor c-Myc, also known as MYC, an important oncoprotein known to be upregulated in most human cancers. The encoded protease may also regulate the activation of autophagy. USP36 exhibits elevated expression in some breast and lung cancers.,Ubiquitin carboxyl-terminal hydrolase 36
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Molecular Weight
- observerd band 125kDa
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Gene ID
- 57602
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UniProt
- Q9P275
Target
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