UBE4A antibody (Internal Region)

Catalog No. ABIN7218944

This Rabbit Polyclonal antibody specifically detects UBE4A in ELISA and IHC (p). It exhibits reactivity toward Human and Mouse.

Quick Overview for UBE4A antibody (Internal Region) (ABIN7218944)

Target: UBE4A (Ubiquitination Factor E4A (UBE4A))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBE4A antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-UBE4A Antibody

Binding Specificity: Internal Region

Purpose: UFD2 Polyclonal Antibody

Specificity: UFD2 Polyclonal Antibody detects endogenous levels of UFD2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human UFD2

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for UBE4A

Target: UBE4A (Ubiquitination Factor E4A (UBE4A))

Alternative Name: UFD2

Background: Rabbit Anti-UFD2 Polyclonal Antibody,UBE4B, HDNB1, KIAA0684, UFD2, Ubiquitin conjugation factor E4 B, Homozygously deleted in neuroblastoma 1, Ubiquitin fusion degradation protein 2,The ubiquitination factor E4B with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE4B encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.,Ubiquitin conjugation factor E4 B

Gene ID: 10277

UniProt: O95155