UGDH antibody (AA 360-440)

Catalog No. ABIN7224864

This anti-UGDH antibody is a Rabbit Polyclonal antibody detecting UGDH in WB, ELISA and IHC (p). Suitable for Human, Mouse and Rat.

Quick Overview for UGDH antibody (AA 360-440) (ABIN7224864)

Target: UGDH (UDP-Glucose 6-Dehydrogenase (UGDH))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UGDH antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-UGDH Antibody

Binding Specificity: AA 360-440

Purpose: UDP-GlcDH Polyclonal Antibody

Specificity: UDP-GlcDH Polyclonal Antibody detects endogenous levels of UDP-GlcDH protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human UDP-GlcDH at AA range: 360-440

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for UGDH

Target: UGDH (UDP-Glucose 6-Dehydrogenase (UGDH))

Alternative Name: UDP-GlcDH

Background: Rabbit Anti-UDP-GlcDH Polyclonal Antibody,UGDH, UDP-glucose 6-dehydrogenase, UDP-Glc dehydrogenase, UDP-GlcDH, UDPGDH,The protein encoded by UGDH (UDP-glucose 6-dehydrogenase) converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of UGDH is up-regulated by transforming growth factor beta and down-regulated by hypoxia. Alternative splicing results in multiple transcript variants.,UDP-glucose 6-dehydrogenase

Molecular Weight: observerd band 55kDa

Gene ID: 7358

UniProt: O60701

Pathways: Glycosaminoglycan Metabolic Process