UGDH antibody (C-Term)

Catalog No. ABIN656544

The Rabbit Polyclonal anti-UGDH antibody (Clone RB32083) (ABIN656544) specifically detects UGDH in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for UGDH antibody (C-Term) (ABIN656544)

Target: UGDH (UDP-Glucose 6-Dehydrogenase (UGDH))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UGDH antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB32083

Product Details anti-UGDH Antibody

Binding Specificity: AA 465-494, C-Term

Predicted Reactivity: M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This UGDH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 465-494 amino acids from the C-terminal region of human UGDH.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: UGDH Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for UGDH

Target: UGDH (UDP-Glucose 6-Dehydrogenase (UGDH))

Alternative Name: UGDH

Background: The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia. Alternative splicing results in multiple transcript variants.

Molecular Weight: 55024

Gene ID: 7358

NCBI Accession: NP_001171629, NP_001171630, NP_003350

UniProt: O60701

Pathways: Glycosaminoglycan Metabolic Process