UNC5D antibody (AA 160-240)

Catalog No. ABIN7232044

This Rabbit Polyclonal antibody specifically detects UNC5D in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for UNC5D antibody (AA 160-240) (ABIN7232044)

Target: UNC5D (Unc-5 Homolog D (UNC5D))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UNC5D antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-UNC5D Antibody

Binding Specificity: AA 160-240

Purpose: UNC5D Polyclonal Antibody

Specificity: The antibody detects endogenous levels of UNC5D protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human UNC5D protein at AA range: 160-240

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for UNC5D

Target: UNC5D (Unc-5 Homolog D (UNC5D))

Alternative Name: UNC5D

Background: Rabbit Anti-UNC5D Polyclonal Antibody,Netrin receptor UNC5D, Protein unc-5 homolog 4, Protein unc-5 homolog D,Receptor for the netrin NTN4 that promotes neuronal cell survival. Plays a role in cell-cell adhesion and cell guidance. Receptor for netrin involved in cell migration. Plays a role in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. May play a role in apoptosis in response to DNA damage. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (PubMed: 24519068). Mediates cell-cell adhesion via its interaction with FLRT3 on an adjacent cell.,UNC5D

Molecular Weight: observerd band 104kDa

Gene ID: 137970

UniProt: Q6UXZ4