V-SNARE Vti1a (AA 1-80) antibody

Catalog No. ABIN7219712

This Rabbit Polyclonal antibody specifically detects V-SNARE Vti1a in ELISA and WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for V-SNARE Vti1a (AA 1-80) antibody (ABIN7219712)

Target: V-SNARE Vti1a

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details

Binding Specificity: AA 1-80

Purpose: v-SNARE Vti1a Polyclonal Antibody

Specificity: V-SNARE Vti1a Polyclonal Antibody detects endogenous levels of v-SNARE Vti1a protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human v-SNARE Vti1a at AA range: 1-80

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details

Target: V-SNARE Vti1a

Background: Rabbit Anti-v-SNARE Vti1a Polyclonal Antibody,VTI1A, Vesicle transport through interaction with t-SNAREs homolog 1A, Vesicle transport v-SNARE protein Vti1-like 2, Vti1-rp2,Vesicle transport through interaction with t-SNAREs homolog 1A encoded by VTI1A is a member of the family of soluble N-ethylmaleimide-sensitive fusion protein-attachment protein receptors (SNAREs) that function in intracellular trafficking. This family member is involved in vesicular transport between endosomes and the trans-Golgi network. It is a vesicle-associated SNARE (v-SNARE) that interacts with target membrane SNAREs (t-SNAREs). Polymorphisms in this gene have been associated with binocular function, and also with susceptibility to colorectal and lung cancers. A recurrent rearrangement has been found between this gene and the transcription factor 7-like 2 (TCF7L2) gene in colorectal cancers. Alternative splicing results in multiple transcript variants.,Vesicle transport through interaction with t-SNAREs homolog 1A

Molecular Weight: observerd band 23kDa

Gene ID: 143187

UniProt: Q96AJ9