ZBTB33 antibody (AA 100-180)

Catalog No. ABIN7229226

The Rabbit Polyclonal anti-ZBTB33 antibody has been validated for WB and ELISA. It is suitable to detect ZBTB33 in samples from Human and Mouse.

Quick Overview for ZBTB33 antibody (AA 100-180) (ABIN7229226)

Target: ZBTB33 (Zinc Finger and BTB Domain Containing 33 (ZBTB33))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZBTB33 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ZBTB33 Antibody

Binding Specificity: AA 100-180

Purpose: KAISO Polyclonal Antibody

Specificity: The antibody detects endogenous levels of KAISO protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human KAISO protein at AA range: 100-180

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for ZBTB33

Target: ZBTB33 (Zinc Finger and BTB Domain Containing 33 (ZBTB33))

Alternative Name: KAISO

Background: Rabbit Anti-KAISO Polyclonal Antibody,Transcriptional regulator Kaiso Zinc finger and BTB domain-containing protein 33,ZBTB33 (Zinc Finger And BTB Domain Containing 33) encodes a transcriptional regulator with bimodal DNA-binding specificity, which binds to methylated CGCG and also to the non-methylated consensus KAISO-binding site TCCTGCNA. The protein contains an N-terminal POZ/BTB domain and 3 C-terminal zinc finger motifs. It recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. ZBTB33 is a Protein Coding gene. Diseases associated with ZBTB33 include Epithelial Malignant Thymoma and Dendritic Cell Thymoma. Among its related pathways are Wnt Signaling Pathway and Pluripotency.,KAISO

Molecular Weight: observerd band 73kDa

Gene ID: 10009

UniProt: Q86T24