ZNF384 antibody (N-Term)

Catalog No. ABIN7218572

The Rabbit Polyclonal anti-ZNF384 antibody (ABIN7218572) specifically detects ZNF384 in WB and ELISA. The antibody is reactive with Human and Rat samples.

Quick Overview for ZNF384 antibody (N-Term) (ABIN7218572)

Target: ZNF384 (Zinc Finger Protein 384 (ZNF384))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZNF384 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ZNF384 Antibody

Binding Specificity: N-Term

Purpose: Rabbit Anti-ZNF384 Polyclonal Antibody

Specificity: ZNF384 Polyclonal Antibody detects endogenous levels of ZNF384 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human ZNF384

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ZNF384

Target: ZNF384 (Zinc Finger Protein 384 (ZNF384))

Alternative Name: ZNF384

Background: ZNF384, CAGH1, CIZ, NMP4, TNRC1, Zinc finger protein 384, CAG repeat protein 1, CAS-interacting zinc finger protein, Nuclear matrix transcription factor 4, Nuclear matrix protein 4, Trinucleotide repeat-containing gene 1 proteinZNF384 encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7.

Molecular Weight: 64kD

Gene ID: 171017

UniProt: Q8TF68