ZCCHC17 antibody (AA 30-110)

Catalog No. ABIN7223034

This anti-ZCCHC17 antibody is a Rabbit Polyclonal antibody detecting ZCCHC17 in ELISA and IHC (p). Suitable for Human and Mouse.

Quick Overview for ZCCHC17 antibody (AA 30-110) (ABIN7223034)

Target: ZCCHC17 (Zinc Finger, CCHC Domain Containing 17 (ZCCHC17))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZCCHC17 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ZCCHC17 Antibody

Binding Specificity: AA 30-110

Purpose: pNO40 Polyclonal Antibody

Specificity: PNO40 Polyclonal Antibody detects endogenous levels of pNO40 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human pNO40 at AA range: 30-110

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for ZCCHC17

Target: ZCCHC17 (Zinc Finger, CCHC Domain Containing 17 (ZCCHC17))

Alternative Name: pNO40

Background: Rabbit Anti-pNO40 Polyclonal Antibody,ZCCHC17, PS1D, HSPC243, HSPC251, LDC4, Nucleolar protein of 40 kDa, pNO40, Pnn-interacting nucleolar protein, Putative S1 RNA-binding domain protein, PS1D protein, Zinc finger CCHC domain-containing protein 17,Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZCCHC17 (zinc finger, CCHC domain containing 17), also known as PS1D (putative S1 RNA-binding domain protein), Pnn (Pinin)-interacting nucleolar protein or pNO40, is a 241 amino acid protein that associates with both Pinin and the 60S ribosomal subunit. Localizing to nucleolus, ZCCHC17 is ubiquitously expressed and has been suggested to play a role in ribosome maturation and biogenesis. ZCCHC17 contains one CCHC-type zinc finger, a S1 motif domain and exists as two alternatively spliced isoforms that map to human chromosome 1p35.2. Human chromosome 1 spans 260 million base pairs, contains over 3000 genes, comprises nearly 8 % of the human genome and houses a large number of disease-associated genes, including those that are involved in Stickler syndrome, Parkinson's disease, Gaucher disease and Usher syndrome.,Nucleolar protein of 40 kDa

Gene ID: 51538

UniProt: Q9NP64