IL-6 Receptor antibody

Catalog No. ABIN7232333

Product Details anti-IL-6 Receptor Antibody

Target: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL-6 Receptor antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunoprecipitation (IP), ELISA, Flow Cytometry (FACS), Functional Studies (Func)

Purpose: Anti-Human CD126 Monoclonal Antibody, Azide Free Clone B-R6

Specificity: Recognises the Interleukin-6 Ra subunit, IL-6 Ra, IL-6 R, a 80 kDa protein

Immunogen: gp80 transfected CHO cell line,Myeloma X63/AG.8653 x Balb/c spleen cells

Clone: B-R6

Isotype: IgG1 kappa

Biological Activity Comment: Inhibits IL-6 induced proliferation of XG-1 cells

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free

Preservative: Without preservative

Storage: 4 °C

Storage Comment: Stable at +2-8°C for 12 months. For longer storage freeze aliquots.

Target Details for IL-6 Receptor

Target: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Alternative Name: CD126 (IL6R Products)

Background: IL-6R / gp80

Pathways: JAK-STAT Signaling, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints