ABAT antibody
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- Target See all ABAT Antibodies
- ABAT (4-Aminobutyrate Aminotransferase (ABAT))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Monoclonal
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Conjugate
- This ABAT antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Purpose
- GABA transaminase (ABAT) Rabbit mAb
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Monoclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- A synthesized peptide derived from human GABA transaminase (GABA transaminase (ABAT))
- Isotype
- IgG
- Top Product
- Discover our top product ABAT Primary Antibody
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anti-4-Aminobutyrate Aminotransferase (ABAT) (AA 236-500) antibody
ABAT Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-4-Aminobutyrate Aminotransferase (ABAT) antibodyABAT Reactivity: Human WB, IHC (p), IF, ICC, IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-4-Aminobutyrate Aminotransferase (ABAT) (AA 29-300) antibodyABAT Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-4-Aminobutyrate Aminotransferase (ABAT) (AA 29-300) antibodyABAT Reactivity: Human WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-4-Aminobutyrate Aminotransferase (ABAT) (AA 151-250) antibodyABAT Reactivity: Human, Mouse, Rat WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-4-Aminobutyrate Aminotransferase (ABAT) (AA 1-500) antibodyABAT Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-4-Aminobutyrate Aminotransferase (ABAT) (C-Term) antibodyABAT Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-4-Aminobutyrate Aminotransferase (ABAT) (Internal Region) antibodyABAT Reactivity: Human, Mouse, Rat WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-4-Aminobutyrate Aminotransferase (ABAT) (AA 249-500) antibodyABAT Reactivity: Human WB, IHC, ICC Host: Rabbit Polyclonal unconjugated
anti-4-Aminobutyrate Aminotransferase (ABAT) antibodyABAT Reactivity: Human, Mouse, Rat WB, IHC, IF, IC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- ABAT (4-Aminobutyrate Aminotransferase (ABAT))
- Alternative Name
- ABAT (ABAT Products)
- Background
- 4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95 % similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. [provided by RefSeq, Jul 2008],GABA-AT, GABAT, NPD009,Amino acid metabolism,Cancer,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial metabolism_Mitochondrial markers,Neurodegenerative Diseases Markers,Neuroscience,Other Neurological disorders,Signal Transduction,ABAT
- Molecular Weight
- 50kDa
- Gene ID
- 18
- UniProt
- P80404
- Pathways
- Monocarboxylic Acid Catabolic Process
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