ADAM15 antibody

Catalog No. ABIN7265434

This Rabbit Monoclonal antibody specifically detects ADAM15 in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for ADAM15 antibody (ABIN7265434)

Target: ADAM15 (ADAM Metallopeptidase Domain 15 (ADAM15))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This ADAM15 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-ADAM15 Antibody

Purpose: ADAM15 Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human ADAM15

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ADAM15

Target: ADAM15 (ADAM Metallopeptidase Domain 15 (ADAM15))

Alternative Name: ADAM15

Background: The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008],MDC15,Cancer,Cell Adhesion,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Extracellular Matrix_ADAM Protein Family,Invasion and Metastasis,Signal Transduction,Ubiquitin,ADAM15

Molecular Weight: 90,100kDa

Gene ID: 8751

UniProt: Q13444