ALDH6A1 antibody (AA 326-535)

Catalog No. ABIN7265543

The Rabbit Polyclonal anti-ALDH6A1 antibody has been validated for IHC and IF. It is suitable to detect ALDH6A1 in samples from Human.

Quick Overview for ALDH6A1 antibody (AA 326-535) (ABIN7265543)

Target: ALDH6A1 (Aldehyde Dehydrogenase 6 Family, Member A1 (ALDH6A1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALDH6A1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-ALDH6A1 Antibody

Binding Specificity: AA 326-535

Purpose: ALDH6A1 Rabbit pAb

Sequence: VGEAKKWLPE LVEHAKNLRV NAGDQPGADL GPLITPQAKE RVCNLIDSGT KEGASILLDG RKIKVKGYEN GNFVGPTIIS NVKPNMTCYK EEIFGPVLVV LETETLDEAI QIVNNNPYGN GTAIFTTNGA TARKYAHLVD VGQVGVNVPI PVPLPMFSFT GSRSSFRGDT NFYGKQGIQF YTQLKTITSQ WKEEDATLSS PAVVMPTMGR

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 326-535 of human ALDH6A1 (NP_005580.1).

Isotype: IgG

Application Details

Application Notes: IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ALDH6A1

Target: ALDH6A1 (Aldehyde Dehydrogenase 6 Family, Member A1 (ALDH6A1))

Alternative Name: ALDH6A1

Background: This gene encodes a member of the aldehyde dehydrogenase protein family. The encoded protein is a mitochondrial methylmalonate semialdehyde dehydrogenase that plays a role in the valine and pyrimidine catabolic pathways. This protein catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids. Alternate splicing results in multiple transcript variants.,ALDH6A1,MMSADHA,MMSDH,Epigenetics & Nuclear Signaling,RNA Binding,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Amino acid metabolism,ALDH6A1

Molecular Weight: 56kDa/57kDa

Gene ID: 4329

UniProt: Q02252

Pathways: Brown Fat Cell Differentiation