Vasopressin antibody (AA 20-164)

Catalog No. ABIN7265664

This anti-Vasopressin antibody is a Rabbit Polyclonal antibody detecting Vasopressin in WB. Suitable for Human.

Quick Overview for Vasopressin antibody (AA 20-164) (ABIN7265664)

Target: Vasopressin (AVP) (Arginine Vasopressin (AVP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Vasopressin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Vasopressin Antibody

Binding Specificity: AA 20-164

Purpose: AVP Rabbit pAb

Sequence: CYFQNCPRGG KRAMSDLELR QCLPCGPGGK GRCFGPSICC ADELGCFVGT AEALRCQEEN YLPSPCQSGQ KACGSGGRCA AFGVCCNDES CVTEPECREG FHRRARASDR SNATQLDGPA GALLLRLVQL AGAPEPFEPA QPDAY

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-164 of human AVP (NP_000481.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Vasopressin

Target: Vasopressin (AVP) (Arginine Vasopressin (AVP))

Alternative Name: AVP

Background: This gene encodes a member of the vasopressin/oxytocin family and preproprotein that is proteolytically processed to generate multiple protein products. These products include the neuropeptide hormone arginine vasopressin, and two other peptides, neurophysin 2 and copeptin. Arginine vasopressin is a posterior pituitary hormone that is synthesized in the supraoptic nucleus and paraventricular nucleus of the hypothalamus. Along with its carrier protein, neurophysin 2, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis where it is either stored or secreted into the bloodstream. The precursor is thought to be activated while it is being transported along the axon to the posterior pituitary. Arginine vasopressin acts as a growth factor by enhancing pH regulation through acid-base transport systems. It has a direct antidiuretic action on the kidney, and also causes vasoconstriction of the peripheral vessels. This hormone can contract smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. Mutations in this gene cause autosomal dominant neurohypophyseal diabetes insipidus (ADNDI). This gene is present in a gene cluster with the related gene oxytocin on chromosome 20.,AVP,ADH,ARVP,AVP-NPII,AVRP,VP,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Neuroscience,AVP

Molecular Weight: 17kDa

Gene ID: 551

UniProt: P01185

Pathways: cAMP Metabolic Process