ATG9A antibody (AA 180-290)

Catalog No. ABIN7265712

This anti-ATG9A antibody is a Rabbit Polyclonal antibody detecting ATG9A in WB and IF. Suitable for Human.

Quick Overview for ATG9A antibody (AA 180-290) (ABIN7265712)

Target: ATG9A (ATG9 Autophagy Related 9 Homolog A (S. Cerevisiae) (ATG9A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATG9A antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-ATG9A Antibody

Binding Specificity: AA 180-290

Purpose: ATG9A Rabbit pAb

Sequence: WQEVQARIVQ TQKEHQICIH KRELTELDIY HRILRFQNYM VALVNKSLLP LRFRLPGLGE AVFFTRGLKY NFELILFWGP GSLFLNEWSL KAEYKRGGQR LELAQRLSNR I

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 180-290 of human ATG9A (NP_076990.4).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ATG9A

Target: ATG9A (ATG9 Autophagy Related 9 Homolog A (S. Cerevisiae) (ATG9A))

Alternative Name: ATG9A

Background: Phospholipid scramblase involved in autophagy by mediating autophagosomal membrane expansion. Cycles between the preautophagosomal structure/phagophore assembly site (PAS and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 (ATG2A or ATG2B from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion. Also required to supply phosphatidylinositol 4-phosphate to the autophagosome initiation site by recruiting the phosphatidylinositol 4-kinase beta (PI4KB in a process dependent on ARFIP2, but not ARFIP1. In addition to autophagy, also plays a role in necrotic cell death (By similarity.,ATG9A,APG9L1,MGD3208,mATG9,Cancer,Tumor suppressors,Signal Transduction,Cell Biology & Developmental Biology,Autophagy,Ubiquitin,Endocrine & Metabolism,Mitochondrial metabolism,Neuroscience,Neurodegenerative Diseases,Cardiovascular,Heart,ATGs,ATG9A

Molecular Weight: 60kDa/87kDa/94kDa

Gene ID: 79065

UniProt: Q7Z3C6