BACE1 antibody

Catalog No. ABIN7265879

The Rabbit Monoclonal anti-BACE1 antibody has been validated for WB. It is suitable to detect BACE1 in samples from Human.

Quick Overview for BACE1 antibody (ABIN7265879)

Target: BACE1 (Beta-secretase 1 (BACE1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This BACE1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BACE1 Antibody

Purpose: BACE1 Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human BACE1

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for BACE1

Target: BACE1 (Beta-secretase 1 (BACE1))

Alternative Name: BACE1

Background: This gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta peptides are the main constituent of amyloid beta plaques, which accumulate in the brains of human Alzheimer's disease patients. [provided by RefSeq, Nov 2015],ASP2, BACE, HSPC104,Cell Biology & Developmental Biology,Neurodegenerative Diseases,Neurodegenerative Diseases_Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimers Disease,Neuroscience,Ubiquitin,BACE1

Molecular Weight: 70kDa

Gene ID: 23621

UniProt: P56817