BACE2 antibody (AA 240-470)

Catalog No. ABIN7265880

This anti-BACE2 antibody is a Rabbit Polyclonal antibody detecting BACE2 in WB and IF. Suitable for Human.

Quick Overview for BACE2 antibody (AA 240-470) (ABIN7265880)

Target: BACE2 (beta-Site APP-Cleaving Enzyme 2 (BACE2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BACE2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-BACE2 Antibody

Binding Specificity: AA 240-470

Purpose: BACE2 Rabbit pAb

Sequence: AGSGTNGGSL VLGGIEPSLY KGDIWYTPIK EEWYYQIEIL KLEIGGQSLN LDCREYNADK AIVDSGTTLL RLPQKVFDAV VEAVARASLI PEFSDGFWTG SQLACWTNSE TPWSYFPKIS IYLRDENSSR SFRITILPQL YIQPMMGAGL NYECYRFGIS PSTNALVIGA TVMEGFYVIF DRAQKRVGFA ASPCAEIAGA AVSEISGPFS TEDVASNCVP AQSLSEPILW I

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 240-470 of human BACE2 (NP_036237.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for BACE2

Target: BACE2 (beta-Site APP-Cleaving Enzyme 2 (BACE2))

Alternative Name: BACE2

Background: This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer's disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants.,BACE2,AEPLC,ALP56,ASP1,ASP21,BAE2,CDA13,CEAP1,DRAP,Cell Biology & Developmental Biology,Ubiquitin,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,BACE2

Molecular Weight: 42kDa/46kDa/48kDa/50kDa/56kDa

Gene ID: 25825

UniProt: Q9Y5Z0