BACE2 antibody (AA 84-157)

Catalog No. ABIN7145535

Product Details anti-BACE2 Antibody

Target: BACE2 (beta-Site APP-Cleaving Enzyme 2 (BACE2))

Binding Specificity: AA 84-157

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BACE2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human, Rat

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Beta-secretase 2 protein (84-157AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for BACE2

Target: BACE2 (beta-Site APP-Cleaving Enzyme 2 (BACE2))

Alternative Name: BACE2 (BACE2 Products)

Synonyms: AEPLC antibody, ALP56 antibody, ASP1 antibody, ASP21 antibody, BAE2 antibody, CEAP1 antibody, DRAP antibody, 1110059C24Rik antibody, AI850424 antibody, ARP1 antibody, CDA13 antibody, beta-site APP-cleaving enzyme 2 antibody, BACE2 antibody, Bace2 antibody

Background:

Background: Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672.

Aliases: ALP 56 antibody, ALP56 antibody, Asp 1 antibody, ASP1 antibody, ASP21 antibody, Aspartic Like Protease 56 kDa antibody, Aspartic-like protease 56 kDa antibody, Aspartyl protease 1 antibody, BACE 2 antibody, Bace2 antibody, BACE2_HUMAN antibody, Beta Secretase 2 antibody, Beta Site Amyloid Beta A4 Precursor Protein Cleaving Enzyme 2 antibody, Beta-secretase 2 antibody, Beta-site amyloid precursor protein cleaving enzyme 2 antibody, Beta-site APP cleaving enzyme 2 antibody, Down region aspartic protease antibody, Downs Syndrome Region Aspartic Protease antibody, DRAP antibody, Memapsin 1 antibody, Memapsin-1 antibody, Membrane associated aspartic protease 1 antibody, Membrane-associated aspartic protease 1 antibody, Theta-secretase antibody

UniProt: Q9Y5Z0