BRK1 antibody (AA 1-75)

Catalog No. ABIN7265930

The Rabbit Polyclonal anti-BRK1 antibody has been validated for IHC and IF. It is suitable to detect BRK1 in samples from Human.

Quick Overview for BRK1 antibody (AA 1-75) (ABIN7265930)

Target: BRK1 (BRICK1, SCAR/WAVE Actin-Nucleating Complex Subunit (BRK1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BRK1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-BRK1 Antibody

Binding Specificity: AA 1-75

Purpose: BRK1 Rabbit pAb

Sequence: MAGQEDPVQR EIHQDWANRE YIEIITSSIK KIADFLNSFD MSCRSRLATL NEKLTALERR IEYIEARVTK GETLT

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-75 of human BRK1 (NP_060932.2).

Isotype: IgG

Application Details

Application Notes: IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for BRK1

Target: BRK1 (BRICK1, SCAR/WAVE Actin-Nucleating Complex Subunit (BRK1))

Alternative Name: BRK1

Background: Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity.,BRK1,C3orf10,HSPC300,MDS027,hHBrk1,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,BRK1

Gene ID: 55845

UniProt: Q8WUW1

Pathways: RTK Signaling