BRD4 antibody (pSer1083)

Catalog No. ABIN7265947

This Rabbit Monoclonal antibody specifically detects BRD4 in WB. It exhibits reactivity toward Human.

Quick Overview for BRD4 antibody (pSer1083) (ABIN7265947)

Target: BRD4 (Bromodomain Containing 4 (BRD4))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This BRD4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BRD4 Antibody

Binding Specificity: pSer1083

Purpose: Phospho-BRD4-S1083 Rabbit mAb

Cross-Reactivity: Human

Characteristics: Phosphorylated Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1050 to 1150 of human Phospho-BRD4-S1083 (NP_490597.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for BRD4

Target: BRD4 (Bromodomain Containing 4 (BRD4))

Alternative Name: BRD4

Background: The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15,19)(q13,p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described.,BRD4, CAP, HUNK1, HUNKI, MCAP, bromodomain containing 4,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,Signal Transduction,Kinase,Serine/threonine kinases,BRD4

Molecular Weight: 80kDa/88kDa/152kDa

Gene ID: 23476

UniProt: O60885

Pathways: Chromatin Binding, SARS-CoV-2 Protein Interactome