CERKL antibody (AA 359-558)

Catalog No. ABIN7266283

This Rabbit Polyclonal antibody specifically detects CERKL in WB. It exhibits reactivity toward Human.

Quick Overview for CERKL antibody (AA 359-558) (ABIN7266283)

Target: CERKL (Ceramide Kinase-Like (CERKL))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CERKL antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CERKL Antibody

Binding Specificity: AA 359-558

Purpose: CERKL Rabbit pAb

Sequence: LAEKYRWMSP NQRRDFAVVK ALAKLKAEDC EISFLPFNSS DDVQERRAQG SPKSDCNDQW QMIQGQFLNV SIMAIPCLCS VAPRGLAPNT RLNNGSMALI IARNTSRPEF IKHLKRYASV KNQFNFPFVE TYTVEEVKVH PRNNTGGYNP EEEEDETASE NCFPWNVDGD LMEVASEVHI RLHPRLISLY GGSMEEMIPK

Cross-Reactivity: Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 359-558 of human CERKL (NP_001025482.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CERKL

Target: CERKL (Ceramide Kinase-Like (CERKL))

Alternative Name: CERKL

Background: This gene was initially identified as a locus (RP26) associated with an autosomal recessive form of retinitis pigmentosa (arRP) disease. This gene encodes a protein with ceramide kinase-like domains, however, the protein does not phosphorylate ceramide and its target substrate is currently unknown. This protein may be a negative regulator of apoptosis in photoreceptor cells. Mutations in this gene cause a form of retinitis pigmentosa characterized by autosomal recessive cone and rod dystrophy (arCRD). Alternative splicing of this gene results in multiple transcript variants encoding different isoforms and non-coding transcripts.,CERKL,RP26,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Apoptosis,Neuroscience,CERKL

Molecular Weight: 19kDa, 24kDa, 42-62kDa

Gene ID: 375298

UniProt: Q49MI3