Ceramide Kinase-Like (CERKL) (N-Term) antibody

Details for Product No. ABIN2788233, Supplier: Log in to see
Antigen
  • RGD1561057
  • Gm1958
  • Rp26
  • GB19002
  • RP26
  • zgc:162213
  • ceramide kinase like
  • ceramide kinase-like
  • ceramide kinase
  • CERKL
  • Cerkl
  • LOC408315
  • CERK
  • LOC100566923
  • LOC100645684
  • cerkl
Epitope
N-Term
5
4
2
2
2
2
2
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Pig (Porcine), Rabbit, Rat (Rattus)
33
6
4
4
2
2
1
1
1
1
1
1
Host
Rabbit
33
Clonality
Polyclonal
Conjugate
Un-conjugated
1
1
1
Application
Western Blotting (WB)
28
19
8
4
2
2
1
1
Options
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Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human CERKL
Blocking Peptide Blocking peptide for this product available: ABIN974853
Sequence TLDLINLSED HCDIWFRQFK KILAGFPNRP KSLKILLNPQ SHKKEATQVY
Predicted Reactivity Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Pig: 100%, Rabbit: 93%, Rat: 79%
Characteristics This is a rabbit polyclonal antibody against CERKL. It was validated on Western Blot.
Purification Affinity Purified
Antigen
Alternative Name CERKL (CERKL Antibody Abstract)
Background This gene was initially identified as a locus (RP26) associated with an autosomal recessive form of retinitis pigmentosa (arRP) disease. This gene encodes a protein with ceramide kinase-like domains, however, the protein does not phosphorylate ceramide and its target substrate is currently unknown. This protein may be a negative regulator of apoptosis in photoreceptor cells. Mutations in this gene cause a form of retinitis pigmentosa characterized by autosomal recessive cone and rod dystrophy (arCRD). Alternative splicing of this gene results in multiple transcript variants encoding different isoforms and non-coding transcripts.
Alias Symbols: RP26
Protein Size: 532
Molecular Weight 59 kDa
Gene ID 375298
NCBI Accession NM_201548, NP_963842
UniProt Q49MI3
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 532 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-Ceramide Kinase-Like (CERKL) (N-Term) antibody (ABIN2788233) WB Suggested Anti-CERKL Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive ...
Western Blotting (WB) image for anti-Ceramide Kinase-Like (CERKL) (N-Term) antibody (ABIN2788233) WB Suggested Anti-CERKL Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500 Posit...
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