CCKBR antibody (AA 240-335)

Catalog No. ABIN7266340

This Rabbit Polyclonal antibody specifically detects CCKBR in WB. It exhibits reactivity toward Human.

Quick Overview for CCKBR antibody (AA 240-335) (ABIN7266340)

Target: CCKBR (Cholecystokinin B Receptor (CCKBR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCKBR antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CCKBR Antibody

Binding Specificity: AA 240-335

Purpose: CCKBR Rabbit pAb

Sequence: LISRELYLGL RFDGDSDSDS QSRVRNQGGL PGAVHQNGRC RPETGAVGED SDGCYVQLPR SRPALELTAL TAPGPGSGSR PTQAKLLAKK RVVRML

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 240-335 of human CCKBR (NP_795344.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CCKBR

Target: CCKBR (Cholecystokinin B Receptor (CCKBR))

Alternative Name: CCKBR

Background: This gene encodes a G-protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. Alternative splicing results in multiple transcript variants. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors.,CCKBR,CCK-B,CCK2R,GASR,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Endocrine & Metabolism,Endocrine and metabolic diseases,Obesity,Neuroscience,CCKBR

Molecular Weight: 41kDa/48kDa/55kDa

Gene ID: 887

UniProt: P32239

Pathways: Positive Regulation of Peptide Hormone Secretion, Feeding Behaviour