Chordin antibody (AA 686-955)
Quick Overview for Chordin antibody (AA 686-955) (ABIN7266350)
Target
See all Chordin (CHRD) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 686-955
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Purpose
- CHRD Rabbit pAb
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Sequence
- PALAPAKPGG PGRPRDPNTC FFEGQQRPHG ARWAPNYDPL CSLCTCQRRT VICDPVVCPP PSCPHPVQAP DQCCPVCPEK QDVRDLPGLP RSRDPGEGCY FDGDRSWRAA GTRWHPVVPP FGLIKCAVCT CKGGTGEVHC EKVQCPRLAC AQPVRVNPTD CCKQCPVGSG AHPQLGDPMQ ADGPRGCRFA GQWFPESQSW HPSVPPFGEM SCITCRCGAG VPHCERDDCS LPLSCGSGKE SRCCSRCTAH RRPAPETRTD PELEKEAEGS
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Cross-Reactivity
- Mouse, Rat
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Characteristics
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 686-955 of human CHRD (NP_003732.2).
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Chordin (CHRD)
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Alternative Name
- CHRD
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Background
- This gene encodes a secreted protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta-like bone morphogenetic proteins and sequestering them in latent complexes. The encoded protein may also have roles in organogenesis and during adulthood. It has been suggested that this gene could be a candidate gene for Cornelia de Lange syndrome. Reduced expression of this gene results in enhanced bone regeneration. Alternative splicing results in multiple transcript variants. Other alternative splice variants have been described but their full length sequence has not been determined. [provided by RefSeq, Jan 2015],CHRD,Cell Biology & Developmental Biology,Neuroscience,Stem Cells,CHRD
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Gene ID
- 8646
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UniProt
- Q9H2X0
Target
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