COASY antibody

Catalog No. ABIN7266420

This anti-COASY antibody is a Rabbit Monoclonal antibody detecting COASY in WB. Suitable for Human.

Quick Overview for COASY antibody (ABIN7266420)

Target: COASY (CoA Synthase (COASY))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This COASY antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-COASY Antibody

Purpose: CoA synthase (COASY) Rabbit mAb

Cross-Reactivity: Human

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human CoA synthase (COASY).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for COASY

Target: COASY (CoA Synthase (COASY))

Alternative Name: COASY

Background: Coenzyme A (CoA) functions as a carrier of acetyl and acyl groups in cells and thus plays an important role in numerous synthetic and degradative metabolic pathways in all organisms. In eukaryotes, CoA and its derivatives are also involved in membrane trafficking and signal transduction. This gene encodes the bifunctional protein coenzyme A synthase (CoAsy) which carries out the last two steps in the biosynthesis of CoA from pantothenic acid (vitamin B5). The phosphopantetheine adenylyltransferase domain of this bifunctional protein catalyzes the conversion of 4'-phosphopantetheine into dephospho-coenzyme A (dpCoA) while its dephospho-CoA kinase domain completes the final step by phosphorylating dpCoA to form CoA. Mutations in this gene are associated with neurodegeneration with brain iron accumulation (NBIA). Alternative splicing results in multiple isoforms.,COASY, DPCK, NBIA6, NBP, PPAT, UKR1, pOV-2, Coenzyme A synthase,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,COASY

Molecular Weight: 62kDa

Gene ID: 80347

UniProt: Q13057

Pathways: Ribonucleoside Biosynthetic Process