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COASY antibody

COASY Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7255964
$686.00
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  • Target See all COASY Antibodies
    COASY (CoA Synthase (COASY))
    Reactivity
    • 31
    • 14
    • 9
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 24
    • 8
    Rabbit
    Clonality
    • 25
    • 7
    Polyclonal
    Conjugate
    • 21
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This COASY antibody is un-conjugated
    Application
    • 21
    • 10
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human COASY (NP_079509.5).
    Isotype
    IgG
  • Application Notes
    WB 1:500-1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    COASY (CoA Synthase (COASY))
    Alternative Name
    COASY (COASY Products)
    Synonyms
    DPCK antibody, NBP antibody, PPAT antibody, UKR1 antibody, pOV-2 antibody, 1300003G02Rik antibody, Dpck antibody, Ppat antibody, Ukr1 antibody, COASY antibody, zgc:92337 antibody, PPAT/DPCK antibody, Coenzyme A synthase antibody, CoA synthase antibody, bifunctional coenzyme A synthase antibody, Bifunctional coenzyme A synthase antibody, COASY antibody, Coasy antibody, CpipJ_CPIJ008826 antibody, pco122135 antibody, coasy antibody
    Background
    Coenzyme A (CoA) functions as a carrier of acetyl and acyl groups in cells and thus plays an important role in numerous synthetic and degradative metabolic pathways in all organisms. In eukaryotes, CoA and its derivatives are also involved in membrane trafficking and signal transduction. This gene encodes the bifunctional protein coenzyme A synthase (CoAsy) which carries out the last two steps in the biosynthesis of CoA from pantothenic acid (vitamin B5). The phosphopantetheine adenylyltransferase domain of this bifunctional protein catalyzes the conversion of 4'-phosphopantetheine into dephospho-coenzyme A (dpCoA) while its dephospho-CoA kinase domain completes the final step by phosphorylating dpCoA to form CoA. Mutations in this gene are associated with neurodegeneration with brain iron accumulation (NBIA). Alternative splicing results in multiple isoforms.
    Molecular Weight

    Observed_MW: 62 kDa

    Calculated_MW: 62 kDa/65 kDa

    Gene ID
    80347
    UniProt
    Q13057
    Pathways
    Ribonucleoside Biosynthetic Process
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